RANDOMISED-CONTROLLED TRIALS

• Fiber is beneficial in the treatment of childhood constipation. Abstract-PubMed
  Loening-Baucke V, Miele E. Staiano A. Pediatrics. 2004 Mar;113(3 Pt 1):e259-64.
• Use of erythromycin for the treatment of severe chronic constipation in children.
  Bellomo B, Collares EF, Costa-Pinto EA. Braz.J Med Biol.Res. 2003;36(10):1391-6. Full-text available at http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000016&lng=en&nrm=iso
• Comparison of polyethylene glycol 3350 and lactulose for treatment of chronic constipation in children.Abstract-PubMed
  Gremse DA, Hixon J, Crutchfield A. Clin Pediatr (Phila). 2002 May;41(4):225-9.
• Use of cisapride with magnesium oxide in chronic pediatric constipation.
  Ni YH, Lin CC, Chang SH, Yeung CY, Taiwan Pediatric Constipation Study Group. Acta Paediatrica Taiwanica 2001;42(6):345-9.
• The effect of anorectal manometry on the outcome of treatment in severe childhood constipation: a randomized, controlled trial.
  van Ginkel R, Buller HA, Boeckxstaens GE, van Der Plas RN, Taminiau JA, Benninga MA. Pediatrics. 2001 Jul;108(1):E9.
• Cisapride for the treatment of constipation in children.Full-Text
  Bhatnagar SK. Indian Pediatr. 2000 Aug;37(8):917-8.
• Comparison of polyethylene glycol 3350, NF powder and lactulose for treatment of chronic constipation in children Published as Abstract
  Gremse, D. and Hixon J. Journal of Pediatric Gastroenterology & Nutrition 2000 Aug; 31(suppl 2): S131.
• Effect of the dietary fiber glucomannan on chronic constipation in neurologically impaired children.
  Staiano A, Simeone D, Del Giudice E, Miele E, Tozzi A, Toraldo C. J Pediatr. 2000 Jan;136(1):41-5.
• No "demystifying" effect of anorectal manometry in the treatment of childhood constipation Published as Abstract
  van Ginkel, R. Benninga M. A. Buller H. A. van der Plas R. N. and Taminiau J. A. Journal of Pediatric Gastroenterology & Nutrition2000 Aug; 31(suppl 2): S179.
• Cisapride for the treatment of constipation in children: A double-blind study.
  Nurko S, Garcia-Aranda JA, Worona LB, Zlochisty O. J Pediatr. 2000 Jan;136(1):35-40.
• Polyethylene glycol vs. lactitole in the treatment of functional constipation in children: a comparative study Published as Abstract
  Tozzi, A. Pensabene L. Miele E. Di Meo M. Staiano A. and Strisciuglio P. Journal of Pediatric Gastroenterology & Nutrition 2000 Aug; 31(suppl 2): S178.
• Treatment of idiopathic constipation in infants: comparative and randomized study of two mineral waters (60 cases) [Published as a Abstract].
  Constant F, Morali A, Arnaud MJ, Delabriose AM, Thirion F, Matisse N, Wagner M, Dohm JP, Vuillemin JL, Gay G. Journal of Pediatric Gastroenterology & Nutrition 1999;28(5)
• Prospective, randomized trial comparing four biofeedback techniques for patients with constipation.
  Heymen S, Wexner SD, Vickers D, Nogueras JJ, Weiss EG, Pikarsky AJ. Diseases of the Colon & Rectum 1999;42(11):1388-93.
• Intolerance of cow's milk and chronic constipation in children.
  Iacono G, Cavataio F, Montalto G, Florena A, Tumminello M, Soresi M, Notarbartolo A, Carroccio A. New England Journal of Medicine 1998;339(16):1100-4.
• The intestinal ecosystem in chronic functional constipation.
  Zoppi G, Cinquetti M, Luciano A, Benini A, Muner A, Bertazzoni ME. Acta Paediatrica 1998;87(8):836-41.
• The relationship between intake of dietary fiber and chronic constipation in children [Dutch].
  Mooren GCAH, Van DPRN, Bossuyt PMM, Taminiau JAJM, Buller HA. Nederlands Tijdschrift Voor Geneeskunde 1996;140(41):2036-9.
• Cisapride in neurologically impaired children with chronic constipation.
  Staiano A, Del Giudice E, Simeone D, Miele E, Marino A. Digestive Diseases & Sciences 1996;41(5):870-4.
• Biofeedback training in treatment of childhood constipation: a randomised controlled study.[comment].
  van der Plas RN, Benninga MA, Buller HA, Bossuyt PM, Akkermans LM, Redekop WK, Taminiau JA. Lancet 1996;348(9030):776-80.
• [Infantile constipation and Allomin-lactulose. Treatment of infantile constipation in infants fed with breast milk substitutes. A controlled clinical trial of 2 per cent and 4 per cent Allomin-lactulose]. [Danish].
  Hejl M, Kamper J, Ebbesen F, and HC. Ugeskrift for Laeger 1990;152(25):1819-22.
• [Double-blind study of the effectiveness and tolerance of metoclopramide in the treatment of chronic constipation and diverticulosis of the colon]. [Italian]
  Galeone M, Innocenti P, Moise G, Cacioli D, Megevand J, Benazzi E. Minerva Dietologica e Gastroenterologica 1987;33(3):231-4.
• Lubricant versus laxative in the treatment of chronic functional constipation of children: a comparative study.
  Sondheimer JM, Gervaise EP. Journal of Pediatric Gastroenterology & Nutrition 1982;1(2):223-6.

Ongoing Trials

• Internet-based Treatment of Early Childhood Fecal Incontinence.
  Cox, DJ. ClinicalTrials.gov . 2003.
• pilot study to determine the acceptability and effectiveness of reflexology as a treatment of constipation in children.[complete].
  Gordon, J. A. National Research Register. 2003.
• The position of defaecation in children under the age of three suffering from constipation [complete].
  Robertson, J. National Research Register. 2000.
• Pilot Study to Evaluate Effect of Early Psychological Intervention in Children with Chronic Constipation [complete].
  Smith, C. National Research Register. 2003.

 

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